MUSC Health Midlands Division welcomes new CEO

May 9, 2023

Matthew (Matt) Littlejohn, MHA, FACHE, has been named the new Chief Executive Officer of the MUSC Health Midlands Division effective May 1, 2023. The Midlands Division encompasses MUSC Health Columbia Medical Center Downtown, MUSC Health Columbia Medical Center Northeast, MUSC Health Fairfield Emergency and Imaging, MUSC Health Kershaw Medical Center in Camden, and all associated medical practices and affiliates.

Littlejohn comes to MUSC Health from Community Health Systems in North Carolina where he served as Network CEO. This system includes Lake Norman Regional Medical Center, Davis Regional Medical Center and an extensive outpatient network.

“It is an honor to come back to the community that helped mold me into the leader I am today,” said Matt Littlejohn, MHA, FACHE, MUSC Health CEO – Midlands Division. “Serving as CEO, I’m excited to lead our care team members in providing excellent healthcare and offering a space where our patients feel valued and rely on us for all their health needs.

A native of Columbia, Littlejohn brings with him a strong record of operational success, excellent relational skills and a passion for building highly effective care teams in community hospital settings. He has been credited with impressive programmatic and volume growth in his previous market.

“We are looking forward to welcoming Matt to the MUSC Health family. We are excited about the leadership and passion he will bring to our Midlands Division as we continue to improve health and maximize quality of life through education, research and patient care,” said Patrick J. Cawley, M.D., MUSC Health CEO and Vice President for Health Affairs, University.

“This is an exciting announcement for the Midlands Division and the entire MUSC Health system. Matt is an excellent fit for this role, and we are thrilled to have him leading the team,” said Matthew Severance, MUSC Health Chief System Development and Affiliations Officer.

Littlejohn attended the University of South Carolina as an undergraduate and received a master’s degree in Health Administration from MUSC. He began his career at Roper St. Francis in Charleston before serving the Bon Secours ministry in Greenville and prior to joining Community Health Systems.

About MUSC

Founded in 1824 in Charleston, MUSC is the state’s only comprehensive academic health system, with a unique mission to preserve and optimize human life in South Carolina through education, research and patient care. Each year, MUSC educates more than 3,200 students in six colleges – Dental Medicine, Graduate Studies, Health Professions, Medicine, Nursing and Pharmacy – and trains more than 900 residents and fellows in its health system. MUSC brought in more than $298 million in research funds in fiscal year 2022, leading the state overall in research funding. MUSC also leads the state in federal and National Institutes of Health funding, with more than $220 million. For information on academic programs, visit

As the health care system of the Medical University of South Carolina, MUSC Health is dedicated to delivering the highest-quality and safest patient care while educating and training generations of outstanding health care providers and leaders to serve the people of South Carolina and beyond. Patient care is provided at 16 hospitals (includes owned and affilated), with approximately 2,700 beds and four additional hospital locations in development; more than 350 telehealth sites and connectivity to patients’ homes; and nearly 750 care locations situated in all regions of South Carolina. In 2022, for the eighth consecutive year, U.S. News & World Report named MUSC Health University Medical Center in Charleston the No. 1 hospital in South Carolina. To learn more about clinical patient services, visit

MUSC has a total enterprise annual operating budget of $5.1 billion. The nearly 26,000 MUSC family members include world-class faculty, physicians, specialty providers, scientists, students, affiliates and care team members who deliver groundbreaking education, research, and patient care.