Understanding the risks of misusing prescription drugs

February 23, 2026

Prescription medications play an important role in treating pain, anxiety and other health conditions when used exactly as directed. However, misusing prescription drugs can quickly lead to dependence, overdose or dangerous interactions. The South Carolina Department of Behavioral Health and Developmental Disabilities’ Office of Substance Use Services (OSUS) is encouraging South Carolinians to better understand how everyday medication misuse can increase serious health risks.

“Prescription drugs are safe when used as prescribed, but misuse can be dangerous,” said Michelle Nienhius, Manager of Prevention and Intervention Services for OSUS. “Taking more than directed, using someone else’s medication or mixing prescriptions with alcohol or other drugs can have life-threatening consequences.”

OSUS warns that opioids, benzodiazepines and stimulants are among the medications most often involved in misuse. Mixing opioids or benzodiazepines with alcohol or other depressants can slow breathing to dangerous levels, while combining stimulants with other substances can strain the heart and mask warning signs of overdose.

Proper storage and disposal of medications are also critical to preventing misuse. Unsecured medications in the home increase the risk of theft, accidental ingestion or misuse by others, including children and teens. OSUS encourages residents to store medications in locked locations and dispose of unused prescriptions at authorized drop-off sites rather than keeping them “just in case.” More data and information are available at justplainkillers.com.

“Medication safety is a shared responsibility,” Nienhius said. “Simple steps like locking up prescriptions, following directions carefully and asking questions can help protect families and communities.”

For more information about prescription drug safety, overdose prevention and available resources, visit daodas.sc.gov.

About the South Carolina Department of Behavioral Health and Developmental Disabilities’ Office of Substance Use Services
The Department of Behavioral Health and Developmental Disabilities’ Office of Substance Use Services (OSUS) ensures the availability and quality of a continuum of substance use services to improve the health status, safety and quality of life of individuals, families and communities across South Carolina. For more information, visit daodas.sc.gov.