Mark Murphy Named Chief Financial Officer for Collexis Holdings, Inc.

April 22, 2008

COLUMBIA, SC – April 22, 2008 – Collexis Holdings, Inc., a leading developer of high definition search and knowledge discovery software, announced today that Mark Murphy has been named the company’s chief financial officer. With more than 30 years of public financial management expertise, Murphy will be responsible for all of Collexis’ accounting operations, including financial reporting and corporate governance, internal controls (SOX) and compliance.

Prior to joining Collexis, Murphy served as the senior vice president of finance for PCA International, Inc., where he directed all finance and treasury functions for the multi-million dollar retail photography business that operated over 2,000 studios in Wal-mart stores in six countries.

He was previously employed with the Kellogg Company where he served in several leadership roles, including director of operations for Kellogg Snacks DSDD. In that position, Murphy directed supply chain efforts and was responsible for product forecasting, deployment and tracking. As the CFO of the Kellogg Company Warehouse Club and Specialty Products business units, he managed strategic planning and analysis, trade spending, business and financial reporting and a variety of other financial efforts.

“We’re excited to welcome Mark to our team,” said Collexis CEO Bill Kirkland. “His financial and public markets expertise will provide an invaluable resource for our company. We look forward to his financial leadership during this time of Collexis’ global expansion.”

A graduate of Ohio University, Murphy has held leadership positions with other large corporations, including Keebler Company, President Baking Company and Price Waterhouse.

About Collexis Holdings, Inc.

Collexis Holdings, Inc., a leading developer of high definition search and knowledge discovery software since 1999, is headquartered in Columbia, South Carolina (USA) with operations in Cincinnati, Ohio, Geldermalsen, the Netherlands and Cologne, Germany. Collexis now offers the world’s first pre-populated professional social network for life science researchers,

Collexis’ proprietary technology builds conceptual profiles of text, called Fingerprints, from documents, Websites, emails and other digitized content and matches them with a comprehensive list of pre-defined “fingerprinted” concepts to make research results more relevant and efficient. This matching of concepts eliminates the ambiguity and lack of priority associated with word searches. The results are often described as “finding needles in many haystacks.”

Through this novel approach, Collexis can build unique applications to search, index and aggregate information as well as prioritize, trend and predict data based on sources in multiple industries without the limitations of language or dialect.

Collexis’ current clients in the public, private and academic sectors include the Mayo Clinic; Johns Hopkins University; the University of California, San Francisco; the University of South Carolina; Erasmus University Library; Bristol-Myers Squibb; Lockheed Martin; the World Health Organization; Wellcome Trust; the National Institutes of Health; and the U.S. Department of Defense.

Shares of Collexis common stock are traded under the symbol CLXS on the OTC Bulletin Board (OTC BB).

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Some of the statements made in this press release may constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are based on management’s current expectations and include known and unknown risks, uncertainties and other factors, many of which the company is unable to predict or control, that may cause the company’s actual results or performance to differ materially from any future results or performance expressed or implied by such forward-looking statements. These statements involve risks and uncertainties. These risks and uncertainties are in addition to other factors detailed from time to time in the company’s filings with the SEC, including the section entitled “Risk Factors” in its transition report on Form 10-KSB for the period ended June 30, 2007, as amended. The company cautions investors that any forward-looking statements made by the company are not necessarily indicative of future performance. The company is not responsible for updating the information contained in this press release beyond the published date, or for changes made to this document by wire services or Internet services.